Compatibility Reference

Do NOT Combine 
 
 
 
 A 
 B 
 Reason 
 
 
 
 
 SIBO yogurt 
 Herbal antimicrobials (berberine, oregano, allicin, neem) 
 Antimicrobials kill the yogurt's beneficial strains indiscriminately 
 
 
 SIBO yogurt 
 Berberine specifically 
 Berberine blocks the yogurt's benefits (confirmed by Davis's Inner Circle) 
 
 
 NAC / serrapeptase 
 Ca, Zn, Fe, Mg supplements 
 Minerals reinforce biofilm matrix. Avoid within 3 hours. Trace amounts in capsule filler (~20-30mg) are negligible and fine. 
 
 
 MotilPro / 5-HTP 
 SSRIs / MAO inhibitors 
 Serotonin syndrome risk 
 
 
 Non-enteric-coated oregano oil 
 Empty stomach (with reflux) 
 Worsens reflux — use enteric-coated only 
 
 
 Elemental diet 
 Antimicrobials 
 Diet starves bacteria dormant; antimicrobials need active replicating bacteria to work 
 
 
 Activated charcoal 
 Any supplement or food 
 Charcoal binds everything indiscriminately. Must be 2+ hours away from all other supplements and food. 
 
 
 
 Safe Together 
 
 
 
 A 
 B 
 Why 
 
 
 
 
 SIBO yogurt 
 Iberogast + ginger + LDN 
 Different mechanisms, no conflict. Prokinetics support motility; yogurt kills bacteria via bacteriocins. 
 
 
 SIBO yogurt 
 NAC + serrapeptase 
 Biofilm disruptors don't kill bacteria — they strip shields, giving yogurt's bacteriocins better access to exposed SIBO bacteria. Yogurt strains unharmed. 
 
 
 NAC + serrapeptase 
 Berberine + allicin 
 Exposed bacteria getting hit by antimicrobials — this is the intended combo for Phase 3. 
 
 
 Iberogast 
 LDN + ginger 
 Three prokinetics with different mechanisms — can be combined for greater effect. 
 
 
 Multiple prokinetics 
 Each other 
 Different mechanisms of action. Combining amplifies MMC support. 
 
 
 ACV 
 All supplements 
 Supports stomach acid environment. No conflicts. 
 
 
 Activated charcoal 
 Nothing within 2 hours 
 Only use for die-off symptom management, well-spaced from everything else. 
 
 
 
 Phase-by-Phase Compatibility 
 
 
 
 Phase 
 Yogurt 
 Biofilm Disruptors 
 Herbal Antimicrobials 
 Prokinetics 
 
 
 
 
 Phase 1 (Weeks 1-6) 
 ✅ 
 ✅ (from week 2) 
 ❌ 
 ✅ 
 
 
 Phase 2 (Weeks 7-8) 
 ✅ 
 ✅ 
 ❌ 
 ✅ 
 
 
 Phase 3 (Weeks 9-14) 
 ❌ 
 ✅ 
 ✅ 
 ✅ 
 
 
 Phase 4 (Week 15+) 
 ✅ 
 ❌ 
 ❌ 
 ✅